Prof. Maud Kamatenesi Mugisha holds a Doctor of Philosophy in Medical Ethnobotany and Ethnopharmacology, a Master of Science in Environment and Natural Resources Management, a Postgraduate Diploma in Education, a Bachelor of Science Degree (Botany and Zoology) from Makerere University and numerous Certificates.

She was recruited as a Teaching Assistant in the Faculty of Science at Makerere from 1996 to 1998. She spearheaded the restructuring of Makerere University into schools and Colleges and provided oversight roles to restructuring Makerere University to present-day academic development and structures.

From 1998 until 2000, she served as Lecturer and Head of Department, at Uganda Fisheries Training Institute in Entebbe.

She later serves as the Head of Fisheries Extension Education and Administration, Fisheries Training Institute, Entebbe. From February 2011 until May 2014, served as the Dean of the School of Biosciences, College of Natural Sciences at Makerere University.

She oversaw the school networks and collaborations, mainly sponsorships of Carnegie Corporation of New York, SIDA Sweden, Madhivani Foundation, Sports Scholarships of Uganda National Sports Council, NAPRECA (Natural Products Research Network for East and Central Africa that were mainly from DAAD), Lake Victoria Environment Management Program (LVEMP) and other external student sponsorships for undergraduate and postgraduate Students.